{"@context":"http://iiif.io/api/presentation/3/context.json","id":"https://arizona.aviaryplatform.com/iiif/d21rf5mg4d/manifest","type":"Manifest","label":{"en":["Arthritis: Fighting Back"]},"logo":"https://d9jk7wjtjpu5g.cloudfront.net/organizations/logo_images/000/000/038/original/university-libraries-logo-2x.png?1711560609","metadata":[{"label":{"en":["Publisher"]},"value":{"en":["KGUN"]}},{"label":{"en":["Rights Statement"]},"value":{"en":["Copyright held by University of Arizona Libraries."]}},{"label":{"en":["Source"]},"value":{"en":["Jay Rochlin videocassettes, box 1, tape 4"]}},{"label":{"en":["Agent"]},"value":{"en":["Rochlin, Jay (producer)"]}},{"label":{"en":["Date"]},"value":{"en":["1978-04-24"]}},{"label":{"en":["Coverage"]},"value":{"en":["Arizona--Tucson"]}},{"label":{"en":["Language"]},"value":{"en":["English"]}},{"label":{"en":["Description"]},"value":{"en":["Investigative report on arthritis, including profiles of people living with the disease."]}},{"label":{"en":["Format"]},"value":{"en":["U-Matic"]}},{"label":{"en":["Identifier"]},"value":{"en":["MS673.004 (uid)"]}},{"label":{"en":["Relation"]},"value":{"en":["Jay Rochlin videocassettes (part of)"]}},{"label":{"en":["Type"]},"value":{"en":["Interviews"]}}],"summary":{"en":["Investigative report on arthritis, including profiles of people living with the disease."]},"requiredStatement":{"label":{"en":["Attribution"]},"value":{"en":["Copyright held by University of Arizona Libraries."]}},"provider":[{"id":"https://arizona.aviaryplatform.com/aboutus","type":"Agent","label":{"en":["University of Arizona Libraries"]},"homepage":[{"id":"https://arizona.aviaryplatform.com/","type":"Text","label":{"en":["University of Arizona Libraries"]},"format":"text/html"}],"logo":[{"id":"https://d9jk7wjtjpu5g.cloudfront.net/organizations/logo_images/000/000/038/original/university-libraries-logo-2x.png?1711560609","type":"Image"}]}],"thumbnail":[{"id":"https://d9jk7wjtjpu5g.cloudfront.net/collection_resource_files/thumbnails/000/160/836/small/azu_ms673-004_a.mp4_1654717304.jpg?1654717305","type":"Image","format":"image/jpeg"}],"items":[{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836","type":"Canvas","label":{"en":["Media File 1 of 1 - azu_ms673-004_a.mp4"]},"duration":1630.55,"width":640,"height":360,"thumbnail":[{"id":"https://d9jk7wjtjpu5g.cloudfront.net/collection_resource_files/thumbnails/000/160/836/small/azu_ms673-004_a.mp4_1654717304.jpg?1654717305","type":"Image","format":"image/jpeg"}],"items":[{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/content/1","type":"AnnotationPage","items":[{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/content/1/annotation/1","type":"Annotation","motivation":"painting","body":{"id":"https://aviary-p-arizona.s3.wasabisys.com/collection_resource_files/resource_files/000/160/836/original/azu_ms673-004_a.mp4?1654717288","type":"Video","format":"video/mp4","duration":1630.55,"width":640,"height":360},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836","metadata":[]}]}],"annotations":[{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448","type":"AnnotationPage","label":{"en":["MS673-004 [Transcript]"]},"items":[{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/1","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Arthritis is everybody's disease in some way it does, or will affect every one of us. During the next 30 minutes, we'll share the insights of person stricken, learn from involved doctors, what's being done today, and what we may hope for in the future and witness the surgical implant of an artificial wrist. This program will not entertain you. It may frighten you. But it will show you what persons who have arthritis and their doctors are doing to fight back.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=42.0,79.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/2","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: He's he'll be 12 in May. And he likes school real well. He plays a clarinet in the band. Well, he started limping in his one leg and he kept running a low grade fever of about 99 degrees. They start taking tests and found out that he his tests weren't right, you know, and that something was going on. And it just took a while for it to show up.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=80.0,110.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/3","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Arthritis is the biggest crippling disease in the country. And Arizona has more than its share. Tucson has the highest per capita incidence of arthritis in the country. But even though this is the biggest crippling disease in the country, many, many medical schools, just don't let me start that again. Many medical schools just don't pay much attention to it. Yeah,","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=111.0,134.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/4","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: I'm afraid that's all too true. There are at least 20 medical schools in the United States that have essentially no formal program and arthritis training in their curriculum.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=135.0,151.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/5","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Yeah, I was hopeful that it was only an overnight thing, you know, it'll eventually work its way out or whatever. Hopefully that it was an error in diagnosis. And","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=152.0,163.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/6","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: we've have 10 times the incidence of arthritis in Tucson that the rest of the country has, and the students who leave our program are going to be seeing patients with arthritis and they've got to know something about it.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=164.0,181.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/7","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: I've been very fortunate in that. My arthritis has been quiet or in remission now for a long time. So I do now have a very good energy level and I am very active and I'm on many committees both nationally and locally. And in Arizona. I can maintain a full time job. Keep a very lovely home. I have many hobbies I like to fish. I like to sail we used to do a lot of sailing when we were on the coast. I feel very fortunate in spite of my long term illness.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=182.0,216.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/8","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Patients move selectively to the Tucson area because they believe either the living is easier for an individual who might be crippled. Or I think there's a quite a strong belief that the that our climate is very good for arthritis. I'm not sure that it makes a difference. But no matter. Patients with arthritis move to Tucson, by the way, everybody's moving to Tucson right now. And that includes in about a proper ratio doctors, but the doctors are not selected for prior knowledge about arthritis.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=217.0,246.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/9","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: I first was diagnosed with rheumatoid arthritis at the age of seven, back in Pennsylvania, and I came out to Arizona at the age of 19 to go to the university and my arthritis was fairly well progressed by that time.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=247.0,266.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/10","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Every day more and more research coming out as to the basic pathological process or disease process that is occurring in these disease joints. We're also becoming more aware that in certain arthritis it's not just the joint that's affected, but the entire body. In fact rheumatoid arthritis is almost like a malignancy without death. It'll do anything a cancer will but does it slower and more painful.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=267.0,292.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/11","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: I have something for my hair, but I'm not. I know the front but I can't do quite The back yet to have some way, they're going to have to fix it so I can get to the back because my arms are not that stable enough. I can't reach up to get the back","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=293.0,327.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/12","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: because we don't have a cure for arthritis, because arthritis is painful, and crippling people will resort to anything. If somebody comes to your door knocks on the door and says I have a cure for arthritis, if you got the kind of pain that can go with arthritis, you're likely to try anything. If you can see your fingers being crippled, if you can no longer do the things that you used to do, and you begin to become afraid of your ability to earn a living. If you're a woman, you'd be come afraid of being able to take care of the children do the housework. And so you'll try anything, even though you don't really believe hope springs eternal. And so you try.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=328.0,371.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/13","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: I went to an orthodontist, and he sent me to another dentist, who did a body chemistry on Greg. And they took a hair analysis and a blood analysis and then they do a chart. And you have highs and lows and what you're with. With your diet. They tried to I guess, bring down the highs. And then with different types of supplements, they tried to bring up the lows and kind of balance it all out. Well, I","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=372.0,402.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/14","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: think it's very important for patients who have arthritis to consult a physician or physician who is knowledgeable in the treatment of arthritis and many physicians are. We don't always need the specialized care as a rheumatologist such as myself, but sometimes we need consultation with one, many general practitioners internists and pediatricians or have good understanding of of disease. The important thing is that they begin on a good treatment program, that they understand the disease that they have, that if they don't understand they demand an explanation. And then that they work very hard with the doctor, with the physical therapist with the team that is caring for them, and try to comply with the medications and to have regular follow up.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=403.0,454.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/15","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: I'm the Director of Education for the Southwest Arthritis Center and considerable amount of my time is spent on developing patient education classes. So the emphasis is more and more on helping the patient understand the disease process.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=455.0,476.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/16","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: The job that really has to be done. And I think it's a finite one, I think I think we've got a few years work ahead of us. And then we'll move on to another phase of care is to teach patients how to get to health care, and teach the health care workers how to deal with the patients with arthritis who are coming in, in numbers and with problems that they've never seen before in the communities they lived in before they moved to Tucson.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=477.0,500.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/17","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: We have commonly tried to describe the treatment of arthritis as a pyramid. And like any building structure a pyramid is is built on a foundation and the foundation really is the most important part. The foundation requires a thorough medical history and physical examination. It may require some specialized laboratory tests X rays, it requires an understanding of what the patient has, if the patient and the family doesn't understand about the arthritis then they can't combat it effectively. And it requires adequate rest physical therapy exercise, it has to be a special program and then the celestial weights which are aspirin derivatives or aspirin itself are used in very special way. This is the foundation this is what we start with. And then after that if if these methods are not effective, or are toxic for some reason, we still work with the foundation but we begin to add more expensive, more toxic type of drugs, trying to work with the safest and the least toxic first. And so as we work up the pyramid, we begin to use some drugs such as the newer super aspirin or aspirin substitute drugs, Motrin, or to lectin or an approximate or now fawn, or IndusInd are some of the drugs that you have heard about. These are also anti inflammatory drugs have painkilling effects and anti inflammatory effects. Just like aspirin many of those Tylenol one of these no Tylenol is not. Tylenol is a drug, which is a painkiller, but it has no end. Tai inflammation effect. And so why it's an adjunct for the pain of arthritis, it does nothing for the arthritis itself.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=501.0,606.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/18","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Now moving up the ladder,","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=607.0,608.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/19","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: well, if these drugs aren't effective, then we go on to drugs such as some of the drugs that have been used to fight malaria in the past Plaquenil is the one most commonly used. And then gold. Penicillin mean. And if these are effective, we begin to start using things such as steroids, cortisone like drugs. And in very severe cases, or patients who have certain complications, we may even use anti cancer drugs. Also, as we're working up the pyramid, the use of surgery comes in, not right at the very bottom. But as the disease progresses, often in rheumatoid arthritis, we have to use surgery as an adjunct to the medical therapy. And we're trying to avoid having to do this but sometimes we just can't do a good enough job with medications alone.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=609.0,659.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/20","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: We went to the hospital for some other reasons he had kidney trouble. And then they they get Dr. Gall and got a hole over and then Dr. volts, talked to her and he said while we can fix you off like new?","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=660.0,674.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/21","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Well, I think surgery is a very significant advancement as far as the treatment of the arthritic patient, but it should be pointed out that the patient is only an appropriate candidate if he exhibits far advanced, arthritic change to the joint. This is not a type of treatment that should be offered to the patient with early changes. This is more or less the last ditch approach so to speak.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=675.0,698.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/22","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Could you describe some of the joints you've developed here for","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=699.0,701.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/23","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: us? Well, in the past five years that I've been associated with the medical center, we've been busily working on several other joints, we developed the artificial risk prosthesis, which was the first one of this type successfully implanted in this country, there are presently two artificial risk prostheses throughout the world. Within the last two years, we've designed and successfully implanted a new type of artificial elbow, the first artificial elbow was designed and inserted into a patient in 1970. But one of the problems that was observed with some of the earlier designs was a high percentage of loosening of the implant. And when this condition arises, the patient has a good deal of pain. The intent of our design was to improve upon the motion which would be permissible at the elbow, and also to diminish the stresses, which can be placed upon the artificial device and thus hopefully, less than the number of cases in which loosening is seen. One of the other projects that we've been working on is the development of an artificial ankle. And I might show you, for instance, how a normal ankle functions. The long bone, which I have in my right hand represents the tibia and fibula, and they're the main weight bearing structures in the lower extremity. And this of course, is the foot and where the two come together as we know we have the ankle joint and it moves essentially in this fashion. Now to show you conceptually how an artificial joint might be inserted, we would take a component which would resurface the joint surface of the long bone and secure it to the bone using a white cement material, and then insert a comparable component into the foot and the two would then be brought together and hopefully would allow a good arc of motion, which was pain free to the patient thus restoring a greater degree of function to the ankle.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=702.0,828.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/24","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Dr. Waltz would like to take a closer look at the wrist and the wrist a surgical procedure can you describe that for us?","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=829.0,836.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/25","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Be happy to the surgical approach to inserting an artificial wrist is identical in concept to the insertion of any of these other artificial joints that I've just discussed. A surgical incision is made over the part to be replaced and generally tendons and muscles are pulled to one side without detaching the ease and a small segment of bone is then taken from the joint which is badly destroyed. This then allows a sufficient amount of space to insert the new component parts. These are then secured by mixing a cement comparable to dental cement. In the operating room. This is inserted in pretty much of a putty state, and it sets within a period of about eight to 10 minutes and becomes very hard and holds the component parts very securely to the bone. The two parts are then reduced or brought into contact with one another and the wound is then sutured shut Add in within a period of several days the patient is allowed to begin moving the joint which has been operated upon","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=837.0,905.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/26","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: listening to talks all sounds too good to be true. Do things go wrong?","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=906.0,911.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/27","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Yes, they definitely do. As with so many things in life, nothing is 100% certainty in this type of surgery. It is however, without doubt the most successful approach to the badly destroyed arthritic joint. But nonetheless, two problems can be identified, which the patient shouldn't be aware of. One is the fact that because these parts are held in place with a Smith material, this segment can be broken loose from the patient skeleton. And when this occurs, the patient perceives pain. And since this has generally been the reason for the operation in the first place, this then represents a failure, and the patient then has to have the part re cemented. This often occurs when the patient is too vigorous in his activities. Following this type of surgery, some individuals may attempt to play tennis with an artificial knee, and may actually put too much stress upon the knee at any one particular time, fracturing it loose, breaking it loose from the bony support. One of the other problems which we try to avoid at all, expense is the development of an infection. And I think by and large, the statistics on the infection rate are becoming better and better because when the English began doing this type of surgery, the infection rate was about 8%. And I think now at most medical centers, the infection rate is somewhere between one and 2%.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=912.0,1009.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/28","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: My arthritis, as far as the joints can deteriorating has, has kind of outpaced some of the some of the technology developments that's frustrating in and then I can I can get into a real poor me trip very easily because of that. Because I have to wait, well, I","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1010.0,1029.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/29","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: think we're going to see the development of better implants as far as their design, I think we're going to see better material used which will allow the prosthesis to last longer and longer. For instance, the hip is pretty well estimated to be capable of lasting with ordinary usage between 30 and 40 years. But in some individuals, this isn't good enough. For instance, if this type of approach were used in a young arthritic horse who was severely disabled, that individual might have need for implants, which would last 40 or 50 years, so to speak.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1030.0,1066.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/30","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Our own research is funded primarily by private funds from the patients who've had arthritis in the past and have supported the institute to the degree it is at the present time. Our institute has both clinical and basic research going we work in the treatment of the arthritis with various new drugs and new approaches to it. And in addition, where other we have another group, or the same group, who are basic research, people who spend their time in the laboratory, such as Mr. Stanfield. Well, in the cells that are that you see on the film, we are taken from human subjects who have had arthritis, they were taken primarily at the time of surgery, when we went in to replace the joint or to help correct a deformity of the arthritis, the cells were then what we call x planet are taken out of the body put into media, like a garden and allowed to grow. We feel that somewhere in that material is the answer to rheumatoid arthritis.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1067.0,1133.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/31","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: But I think we've just scratched the surface. As far as drugs available, we have quite a few drugs that I've mentioned, and some other ones that are a little newer that I haven't mentioned. But there are now with 30 million people in the United States suffering from arthritis. It's obvious, obviously very important that we find some drugs to treat the arthritis with and particularly when patients have side effects or, or have drugs are not effective. And so now, many universities, many private groups are doing research in various drugs for many, many drug companies and looking at their effect on arthritis. Just to give you an example of a few. There's been a lot of publicity about female hormones and their effect on arthritis. And there are some very early studies going on. And we don't understand we know that there are problems with the female hormones and yet, there may be some use if we can work out the right type of analog or something to treat the drug with. There's new drugs that affect the bone primarily rather than than the inflammation. And in fact, we are going to begin a project this July looking at, at one of these, one of these drugs along with several other institutions around the country. There are many new anti inflammatory drugs, some of which have been in use and other countries, some of which are entirely new. And they're trying to be developed to have less side effects to possibly be cheaper, and to be more effective than the drugs that we now have. And so we continue to search for the drug that will suppress the arthritic disease,","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1134.0,1229.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/32","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: like to mention something called the program patient. You know, I read Yeah, this has to do with a patient who has severe arthritis, usually with some fixed deformity that has been trained as an expert, and joint examination, in particular the joint examination of himself or herself. These program patients have become so good at it, they can now meet with a student alone, let the student examine himself or herself, and then feed back to the student exactly what they did right or wrong.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1230.0,1270.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/33","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Well, there are several kinds of arthritis and as as you know, and rheumatoid arthritis, it conceptually the joint is surface is simply digested away as if a bite had been taken out of it. And osteoarthritis, or the wear and tear type of arthritis, these fibers, collagen fibers apparently began to break down so that eventually, what we have, instead of a smooth arcade structure, is a so called fibrillated joint consisting of collagen fibers that are simply sticking up like unmown unmowed grass,","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1271.0,1311.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/34","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: we're about to see a film to tell us while we'll get where we're gonna be saying,","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1312.0,1314.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/35","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Yes, this is a film of normal articular cartilage taken under polarized light microscopy. And what we'll be seeing is an area of the joint about like this, and you'll see bone on one side, you'll see some fibers of collagen, which will be changing colors as the slide is rotated in the movie. These changes in color, tell us the direction of the fibers at given points in the cartilage?","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1315.0,1350.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/36","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: What do you hope, the research to take you in the fight against arthritis?","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1351.0,1354.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/37","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Well, I hope we can better define what it is from a structural point of view.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1355.0,1359.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/38","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: It's not enough, at least it's not enough for the people who are looking over our shoulder from the National Institute of Health, it's not enough to be teaching and demonstrating arthritis care, we've got to prove that what we're doing is effective, right, we got to prove that it changes behavior, we've got to prove that it ends and in better care for the patient.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1360.0,1395.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/39","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: And the first signs of the common forms of arthritis are probably fairly subtle ones such as waking in the morning, feeling unusually stiff, something the way you might feel if you had overdone, an athletic program the day before, and you wake in the morning and find it's very difficult loosening up. Second finding is that it's very hard to say bend a particular joint, and in particular, and frequently, there'll be balanced the joints on both sides of the body, what we'll have the trouble at the same time. The real hallmarks of arthritis. These are these others are relatively minor, early symptoms, but the real hallmarks are swelling, tenderness, increased heat, redness, and finally, loss of motion of any joint in the body.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1396.0,1449.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/40","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: Some people look like they're in pain because they have deformities, and they have crippling and everything. But if the mind is active, if they're mentally and physically active, that pain can be lessened so much. For instance, people might look at me and say, Wow, how can she do it? You know, she looks like she has these problems and all but I am hardly aware that I have any pain because I am very, very mentally and physically active. Everyone gets","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1450.0,1478.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/41","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: depressed even if your normal or abnormal help. But and I think you're allowed to do that. But basically most time, you should think positive and you'll do much better. If you do","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1479.0,1497.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/42","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: this This disease changed his personality and just no time because of the constant pain and he had a lot of pain at first, for first, probably four or five years and often a lot of pain and when you have pain, it changes your personality completely.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1498.0,1516.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/43","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: So I would have to say that if if the arthritis were to suddenly be taken out of my life, I wouldn't miss it. witnessed that event.","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1517.0,1528.999"},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/44","type":"Annotation","motivation":"transcribing","body":{"type":"TextualBody","value":"UNKNOWN SPEAKER: I've seen one arthritic son they, the family gives up usually, you know, there's nothing you can do. But once they see what's happening, you know, and just a little corrective surgery and look at her. She you know, she dances with me now. It's not, you know, no hops or not, she just sways","format":"text/plain"},"target":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836#t=1529.0,1531.0"}]},{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448","type":"AnnotationPage","label":{"en":["English [Transcript]"]},"items":[{"id":"https://arizona.aviaryplatform.com/collections/1985/collection_resources/74841/file/160836/transcript/38448/annotation/45","type":"Annotation","motivation":"subtitling","body":{"type":"TextualBody","value":"https://d9jk7wjtjpu5g.cloudfront.net/file_transcripts/associated_files/000/038/448/original/azu_ms673-004_a.vtt?1654717355","format":"text/vtt","language":"en"},"target":"https://d9jk7wjtjpu5g.cloudfront.net/file_transcripts/associated_files/000/038/448/original/azu_ms673-004_a.vtt?1654717355"}]}]}]}